くすりのしおり

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Published: 4/2009

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Nasanyl Nasal Spray 0.2%
 Active ingredient:
Nafarelin acetate
 Dosage form:
nasal solutions for colorless and transparent, (octagonal container) pink
 Print on wrapping:
Gn-RH誘導体製剤, ナサニール点鼻液

Effects of this medicine

This medicine suppresses ovarian function, by decreasing the GnRH receptors of pituitary.
Usually, used for treatment of endometriosis, improvement of menorrhagia/ lower abdominal pain/ low back pain/ anemia based on shrinking uterine fibroids and uterine fibroids.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you have: an irregular genital bleeding which can not be diagnosed.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 spray (200μg as nafarelin) to the nasal cavity of one side at a time twice a day from first to second day of menstrual cycle. Strictly follow the instructions.
  • If you miss a dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Please take a reliable birth control methods other than the pill such as using a condom.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include hot flash, stiff shoulder, headache, rash, chest pain, eczema, hives, itch and shortness of breath. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • depressed feeling, malaise (general), loss of appetite [depression]
  • nose bleeding, gingival bleeding, subcutaneous bleeding  [thrombocytopenia]
  • malaise (general), loss of appetite, yellowing of the skin or the white of the eyes [hepatic dysfunction, jaundice]
  • menostaxis (excessively long menses), menorrhagia (excessive menstrual bleeding), polymenorrhea [irregular vaginal bleeding]
  • enlarged feeling of abdomen, lower abdominal pain, loss of appetite  [ovarian cyst rupture]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. If you dispose of unused medicines, seek advise of your pharmacist about proper disposal of drugs.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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