くすりのしおり

Internal
Revised: 5/2016

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
HI-Z Tablets 25mg
 Active ingredient:
Gamma oryzanol
 Dosage form:
white tablets, diameter: 8.2 mm, thickness: 4.8 mm
 Print on wrapping:
(Front) OG02, 25mg, ハイゼット錠, Otsuka, ハイゼット錠25mg, (Back) Hi-z tab 25mg, ハイゼット錠25mg

Effects of this medicine

This medicine lowers serum cholesterol mainly by suppressing intestinal absorption of cholesterol and additionally by inhibiting cholesterol synthesis and promoting cholesterol catabolism and excretion. It also modulates endocrine and autonomic nervous systems.
It is usually used to treat hyperlipidemia and to improve various symptoms associated with climacteric disturbance or irritable bowel syndrome.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have liver disorder.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Hyperlipidemia: In general, for adults, take 4 tablets (100 mg of the active ingredient) at a time, three times daily after meals.
  • Somatic symptoms and anxiety, tension, and depression associated with psychosomatic disorder (climacteric disturbance, irritable bowel syndrome): In general, for adults, take 10 to 50 mg of the active ingredient per day. This medicine contains 25 mg of the active ingredient per tablet.
    In any case, the dosage may be adjusted according to your disease, age or symptoms, but for irritable bowel syndrome the dosage is limited to a maximum of 2 tablets (50 mg of the active ingredient) per day. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Follow your doctor’s instructions.
    Regular blood tests may be required while taking this medicine. In that case, undergo the test on your designated date and time.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include sleepiness, nausea/vomiting, diarrhea, skin rash, itch, abnormal skin sensation and flushing. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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